Yi-Shing Ma Selected Research

MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers)

1/2018	Promoter analysis and transcriptional regulation of human carbonic anhydrase VIII gene in a MERRF disease cell model.
4/2014	Effects of carbonic anhydrase-related protein VIII on human cells harbouring an A8344G mitochondrial DNA mutation.
8/2012	The protective roles of phosphorylated heat shock protein 27 in human cells harboring myoclonus epilepsy with ragged-red fibers A8344G mtDNA mutation.
9/2011	Decreased heat shock protein 27 expression and altered autophagy in human cells harboring A8344G mitochondrial DNA mutation.
6/2010	Mitochondrial DNA mutation-elicited oxidative stress, oxidative damage, and altered gene expression in cultured cells of patients with MERRF syndrome.
5/2005	Upregulation of matrix metalloproteinase 1 and disruption of mitochondrial network in skin fibroblasts of patients with MERRF syndrome.
5/2005	High prevalence of the COII/tRNA(Lys) intergenic 9-bp deletion in mitochondrial DNA of Taiwanese patients with MELAS or MERRF syndrome.
1/2002	Clinical phenotype, prognosis and mitochondrial DNA mutation load in mitochondrial encephalomyopathies.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yi-Shing Ma Research Topics

Disease

8	MERRF Syndrome (Myoclonic Epilepsy and Ragged Red Fibers) 01/2018 - 01/2002
3	Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy) 05/2005 - 01/2002
2	Neuromuscular Diseases (Neuromuscular Disease) 08/2012 - 09/2011
2	Mitochondrial Diseases (Mitochondrial Disease) 09/2011 - 10/2009
2	Muscular Diseases (Myopathy) 06/2006 - 01/2002
2	MELAS Syndrome (Syndrome, MELAS) 05/2005 - 01/2002
2	Stroke (Strokes) 05/2005 - 01/2002
1	Hypoxia (Hypoxemia) 01/2022
1	Insulin Resistance 12/2018
1	Neoplasms (Cancer) 02/2014
1	Hyperglycemia 02/2014
1	Colonic Neoplasms (Colon Cancer) 02/2014
1	Colorectal Neoplasms (Colorectal Cancer) 02/2014
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 08/2012
1	Starvation 09/2011
1	Atrophy 06/2010
1	Lactic Acidosis 05/2005
1	Uremia 01/2002
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2002

Drug/Important Bio-Agent (IBA)

11	Mitochondrial DNA (mtDNA)IBA 01/2018 - 01/2002
5	Proteins (Proteins, Gene)FDA Link 12/2018 - 01/2002
2	AntioxidantsIBA 12/2018 - 06/2010
2	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 01/2002
2	Carbonic Anhydrases (Carbonic Anhydrase)IBA 01/2018 - 04/2014
2	StaurosporineIBA 04/2014 - 09/2011
2	HSP27 Heat-Shock ProteinsIBA 08/2012 - 09/2011
2	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 06/2010 - 05/2005
2	Lys Transfer RNAIBA 06/2010 - 05/2005
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2022
1	Sirtuin 3IBA 12/2018
1	Messenger RNA (mRNA)IBA 01/2018
1	ChromatinIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 02/2014
1	Fluorouracil (Carac)FDA LinkGeneric 02/2014
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 08/2012
1	Proteasome InhibitorsIBA 09/2011
1	Sirolimus (Rapamycin)FDA Link 09/2011
1	Aconitate Hydratase (Aconitase)IBA 06/2010
1	ProhibitinsIBA 06/2010
1	EnzymesIBA 06/2010
1	Protease La (Endopeptidase La)IBA 06/2010
1	Voltage-Dependent Anion ChannelsIBA 06/2010
1	Matrix Metalloproteinases (MMPs)IBA 05/2005
1	Complementary DNA (cDNA)IBA 05/2005
1	LipidsIBA 01/2002

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 02/2014